You may have heard of many people taking a baby aspirin daily to "thin the blood." This "thinning" effect is accomplished by shutting down the function of platelets; cell fragments involved in blood clotting. The AGEs mentioned in the previous post negatively affect platelets.
This study shows that when albumin is glycated, it can activate platelets. These activated platelets can then go on to promote heart disease.
Additionally, AGEs have also been implicated in degenerative joint disease. AGEs may collect in joint cartilage to promote the wear and tear typical of osteoarthritis. By now, you can see that diabetes can wreak quite a bit of havoc through the production of AGEs alone.
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